Recombinant Human SERPINC1 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human SERPINC1 protein His33-Lys464 (Accession# P01008) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 462 |
| 蛋白编号 | P01008 |
| 预测分子量 | 74.6 kDa |
| SDS-PAGE | 70-98 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
SERPINC1, also named Antithrombin III or Antithrombin, is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
参考文献:
1.Lu, Zeyuan et al. Clinical science.vol. 131,9 (2017). 2.Mulder, René et al. British journal of haematology vol. 178,2 (2017): 279-285. 3.Wang, Feng et al. Kidney international vol. 88,4 (2015): 796-803.
