Recombinant Human SERPINA12/Vaspin protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human SERPINA12 protein Leu20-Lys414 (Accession# Q8IW75) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 145264 |
| 蛋白编号 | Q8IW75 |
| 预测分子量 | 70.8 kDa |
| SDS-PAGE | 68-88 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
SERPINA12 is also named as Serpin A12 and Visceral adipose tissue-derived serine protease inhibitor (Vaspin). Vaspin is an adipokine belonging to the serpin family, thus also named SERPINA12, with targets in kallikrein 7 and 14 that participates in skin desquamation. Vaspin is a compensatory molecule in obesity and insulin resistance. Vaspin is a newly described adipokine with an insulin sensitizing effect and inhibitory impact on food intake.
参考文献:
1.Kurowska P,Mlyczyńska E,Jurek M, et al. Cells. 2021;10 (7) 2.Wada, Jun et al. Expert opinion on investigational drugs vol. 17,3 (2008): 327-33. 3.Hida, Kazuyuki et al. Proceedings of the National Academy of Sciences of the United States of America vol. 102,30 (2005): 10610-5. 4.Klöting, N et al. Diabetologia vol. 54,7 (2011): 1819-23.
