Recombinant Human SEMA3C protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human SEMA3C protein Gly21-Ser738 (Accession# Q99985) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 10512 |
| 蛋白编号 | Q99985 |
| 预测分子量 | 107.4 kDa |
| SDS-PAGE | 52-56 kDa and 110-130 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
SEMA3C (Semaphorin 3C) is associated with tumor progression and poor prognosis across multiple tumor types, including pancreatic, gastric, prostate, and breast cancer, as well as glioma. It is worth noting that full-length SEMA3C has also been reported as a tumor suppressor factor by suppressing tumor lymphangiogenesis and metastasis.
参考文献:
1. Hao, Jing et al. Nature communications vol. 14,1 2262. 20 Apr. 2023. 2. Xiao, Siyu et al. Oncogene vol. 44,39 (2025): 3679-3693. 3. Liu, Ruoyan et al. Frontiers in oncology vol. 9 1035. 9 Oct. 2019.
