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Recombinant Human S100A8 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3752

Print datasheet

Synonyms

S100A8, CAGA, Calgranulin A, Calgranulin-A, Calprotectin L1L subunit

验证数据展示

  • Purity of Recombinant Human S100A8 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human S100A8 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human S100A8 protein Met1-Glu93 (Accession# P05109) with a rabbit IgG Fc tag at the C-terminus.
基因ID 6279
蛋白编号 P05109
预测分子量 37.1 kDa
SDS-PAGE 38-48 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

S100A8 and S100A9 are Ca2+ binding proteins that belong to the S100 family. Forming a common heterodimer structure S100A8/A9, S100A8 and S100A9 are widely reported to participate in multiple signaling pathways in tumor cells. Meanwhile, S100A8/A9, S100A8, and S100A9, mainly as promoters, contribute to tumor development, growth and metastasis by interfering with tumor metabolism and the microenvironment.

参考文献:

1.   Wang S et.al.(2018) Front Immunol. 9:1298.
2.   Koy M. et al. (2013）Vet Immunol Immunopathol. 155(3):162–70.
3.   Pruenster M. et al. (2016) 167:120-131.
4.   Abtin AEL. et al. (2010). J Invest Dermatol. 130:2423–30.
5.   Shabani F. et al.(2018) 67(10):801-812.