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Recombinant Human MUC17 protein (His Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

C-6*HIS

生物活性

未测试

Cat no : Eg0413

Print datasheet

Synonyms

MUC17, MUC 17, MUC 3, MUC-17, MUC3

验证数据展示

  • Purity of Recombinant Human MUC17 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human MUC17 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human MUC17 protein Arg4131-Leu4390 (Accession# Q685J3-1) with a His tag at the C-terminus.
基因ID 140453
蛋白编号 Q685J3-1
预测分子量 12.6 kDa and 20.5 kDa
SDS-PAGE 17 kDa and 28-38 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

MUC17 is a membrane-bound mucin that provides protection to gut epithelial cells. MUC17 contains about 60 tandem repeats, with each repeat being around 60 aa.Membrane mucins, such as MUC17, function in epithelial cells to provide cytoprotection, maintain luminal structure, provide signal transduction, and confer antiadhesive properties upon cancer cells that lose their apical/basal polarization.

参考文献:

1. Gum JR Jr, Crawley SC, Hicks JW, Szymkowski DE, Kim YS. MUC17, a novel membrane-tethered mucin. Biochem Biophys Res Commun. 2002;291(3):466-475.
2. Pelaseyed T, Bergström JH, Gustafsson JK, et al. The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system. Immunol Rev. 2014;260(1):8-20.