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Recombinant Human MTND protein (rFc Tag)

种属

Human

纯度

>85 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg5924

Print datasheet

Synonyms

ADI1, Acireductone dioxygenase, ADI 1, APL1, ARD



产品信息

纯度 >85 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Human MTND protein Met1-Ala179 (Accession# Q9BV57-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 55256
蛋白编号 Q9BV57-1
预测分子量 47.1 kDa
SDS-PAGE 47-55 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

ADI1(acireductone dioxygenase 1 ) is also named as SIPL, ARD, APL1, HMFT1638, MTCBP-1, FLJ10913, MTCBP1 and belongs to the acireductone dioxygenase (ARD) family. It catalyzes the formation of formate and 2-keto-4-methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).The downregulation of ADI1 protein expression in human prostate cancer specimens argues that ADI1 potentially inhibits the growth that occurs during prostate cancer progression(PMID:17786183). It has 2 isoforms produced by alternative splicing.

参考文献:

1. Hu, Xiaoping, et al. International Journal of Molecular Sciences 24.15 (2023): 12329.

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