Recombinant Human MFAP5 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human MFAP5 protein Ile22-Leu173 (Accession# Q13361-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 8076 |
| 蛋白编号 | Q13361-1 |
| 预测分子量 | 42.9 kDa |
| SDS-PAGE | kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
MFAP5 (microfibril-associated protein 5), also known as MAGP-2, is a secreted extracellular matrix glycoprotein, not a membrane protein in the traditional sense. As a component of microfibrils, it is typically secreted into the extracellular space and assembles onto fibrillin-containing microfibrils, mediating cell-fibril adhesion through binding to integrin αVβ3. Its main functions include elastic fiber assembly, mediating cell signaling (such as the MAPK/ERK pathway), and regulating cell behavior in development and disease.
参考文献:
1. Duan, Yi et al. Oncogene vol. 42,25 (2023): 2061-2073. 2. Li, Jian-Hui et al. Journal of experimental & clinical cancer research : CR vol. 38,1 476. 27 Nov. 2019 3. Li, Qingmei et al. Biochemical and biophysical research communications vol. 507,1-4 (2018): 51-58.
