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Recombinant Human LRG1 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3083

Print datasheet

Synonyms

LRG1, HMFT1766, Leucine-rich alpha-2-glycoprotein, LRG

验证数据展示

  • Purity of Recombinant Human LRG1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

    Purity of Recombinant Human LRG1 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Human LRG1 protein Val36-Gln347 (Accession# P02750) with a rabbit IgG Fc tag at the C-terminus.
基因ID 116844
蛋白编号 P02750
预测分子量 60.4 kDa
SDS-PAGE 60-75 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

LRG1, also known as LRG, is a member of the leucine-rich repeat (LRR) family of proteins, containing eight LRR (leucine-rich) repeats and one LRRCT domain. The gene of LRG1 maps to chromosome 19p13.3, and encodes a 347-amino acid protein with a predicted unmodified molecular weight of 38 kD. The mature form of LRG1 is a secreted glycoprotein which has 312 amino acids and an experimentally determined molecular mass of 45 kD. The LRR family of proteins, including LRG1, have been shown to be involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid.

参考文献:

1. Camilli C, Hoeh AE, et al. (2022) J Biomed Sci. 29(1):6. 
2. Chen C, Zhang J, et al. (2024) Kidney Dis (Basel). 10(3):237-248. 
3. Feng J, Zhan J, Ma S. (2021) Bioengineered. 12(1):8897-8907. 
4. Hong Q, Zhang L, et al. (2019) J Am Soc Nephrol. 30(4):546-562. 
5. He S, Ryu J, et al. (2021) J Clin Invest. 131(24):e148545.