Recombinant Human LILRA1 protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human LILRA1 protein Pro17-Asn461 (Accession# O75019-1) with a His tag at the C-terminus. |
| 基因ID | 11024 |
| 蛋白编号 | O75019-1 |
| 预测分子量 | 49.6 kDa |
| SDS-PAGE | 60-75kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Leukocyte immunoglobulin-like receptor A1 (LILRA1) plays a significant role in the immune system. It is part of the leukocyte immunoglobulin-like receptor (LIR) family. The LILRA1 is predominantly expressed in B cells, where it interacts with major histocompatibility complex class I ligands and contributes to the regulation of immune responses. LILRA1 is involved in various pathways, including the innate immune system and Class I MHC-mediated antigen processing and presentation. It is known to have multiple functions, such as acting as a receptor for class I MHC antigens and potentially playing a role in the recognition and modulation of immune responses.
参考文献:
1. Tedla N. et al. (2011). Tissue Antigens. 77(4):305–316. 2. Hogan LE. et al.(2016). Sci Rep. 6(1):21780. 3. Hirayasu K. et al. (2015). J Hum Genet. 60(11):703–708. 4. An H. et al. (2010). J Rheumatol.37(8):1596–1606.
