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Recombinant Human LECT2 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg3137

Print datasheet

Synonyms

LECT2, hLECT2, LECT 2, LECT-2, Leukocyte cell-derived chemotaxin-2

验证数据展示

  • Purity of Recombinant Human LECT2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human LECT2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human LECT2 protein Gly19-Leu151 (Accession# O14960) with a rabbit IgG Fc tag at the C-terminus.
基因ID 3950
蛋白编号 O14960
预测分子量 40.6 kDa
SDS-PAGE 40-46 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

LECT2 (Leukocyte cell-derived chemotaxin 2) was first isolated by Yamagoe et al in PHA-activated human T-cell leukaemia SKW-3 cells and originally identified as a novel neutrophil chemotactic factor, in 1996. LECT2 is a 16-kDa secreted protein originally identified as a chemotactic factor for neutrophils that can stimulate the growth of chondrocytes and osteoblasts. LECT2 is a pleiotropic and promising hepatokine, and as a latest ligand for Tie1, played a pro-fibrogenic role in the progression of liver fibrogenesis.

参考文献:

1. Xie Y. et al. (2022) J Cell Mol Med. 26(13):3598-3607.
2. Xu M. et al. (2019) Cell. 178(6):1478-1492.e20.
3. Lan F. et al. (2014) Diabetes. 63(5):1649-64.