Recombinant Human LECT2 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human LECT2 protein Gly19-Leu151 (Accession# O14960) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 3950 |
| 蛋白编号 | O14960 |
| 预测分子量 | 40.6 kDa |
| SDS-PAGE | 40-46 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in 30mM Tris, 500mM Arginine, pH 8.0. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile 30mM Tris, 500mM Arginine, pH 8.0. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
LECT2 (Leukocyte cell-derived chemotaxin 2) was first isolated by Yamagoe et al in PHA-activated human T-cell leukaemia SKW-3 cells and originally identified as a novel neutrophil chemotactic factor, in 1996. LECT2 is a 16-kDa secreted protein originally identified as a chemotactic factor for neutrophils that can stimulate the growth of chondrocytes and osteoblasts. LECT2 is a pleiotropic and promising hepatokine, and as a latest ligand for Tie1, played a pro-fibrogenic role in the progression of liver fibrogenesis.
参考文献:
1. Xie Y. et al. (2022) J Cell Mol Med. 26(13):3598-3607. 2. Xu M. et al. (2019) Cell. 178(6):1478-1492.e20. 3. Lan F. et al. (2014) Diabetes. 63(5):1649-64.
