Recombinant Human IL-20RA protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human IL-20RA protein Val30-Lys250 (Accession# Q9UHF4-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 53832 |
| 蛋白编号 | Q9UHF4-1 |
| 预测分子量 | 51.3 KDa |
| SDS-PAGE | 58-75 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Interleukin 20 receptor subunit alpha (IL20RA) belongs to the type II cytokine receptor family. Upon binding to its ligands, such as interleukin (IL)-19, IL-20, and IL-24, IL20RA can form a functional heterodimeric receptor with IL20RB. IL-26, another IL20RA ligand, requires IL20RA and interleukin 10 receptor subunit beta (IL10RB) for signaling.
参考文献:
1. Rutz S. et al. (2014). Nat Rev Immunol. 14:783–95. 2. Blumberg H. et al. (2001). Cell. 104:9–19. 3. Hor S. et al. (2004). J Biol Chem. 279:33343–51.
