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Recombinant Human IL-13RA2 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2579

Print datasheet

Synonyms

IL13RA2, CD213A2, CT19, IL 13 receptor subunit alpha 2, IL 13R

验证数据展示

  • Purity of Recombinant Human IL-13RA2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human IL-13RA2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 CHO-derived Human IL-13RA2 protein Asp27-Arg343 (Accession# Q14627) with a rabbit IgG Fc tag at the C-terminus.
基因ID 3598
蛋白编号 Q14627
预测分子量 63.4 kDa
SDS-PAGE 65-80 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

IL-13RA2 is an inhibitory decoy receptor with a high affinity for IL-13 and diminishes its certain effector functions. IL-13/IL-13RA2 signaling has been repeatedly reported as an excellent therapeutic target for multiple types of cancers. Although many physiological and pathological roles of IL-13/IL-13RA2 signaling transduction have been described, its biological roles and regulatory mechanisms in CSCs remain largely unknown.

参考文献:

1. Hallett, Miranda A et al. Cancer research vol. 72,24 (2012): 6338-43.
2. He, Baoyu et al. Genes & diseases vol. 11,1 495-508. 23 Apr. 2023.
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