Recombinant Human Growth Hormone protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human Growth Hormone protein Phe27-Phe217 (Accession# P01241-1) with a His tag at the N-terminus. |
| 基因ID | 2688 |
| 蛋白编号 | P01241-1 |
| 预测分子量 | 22.9 kDa |
| SDS-PAGE | 20-22 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
Growth hormone (GH) is a heterogeneous polypeptide consisting of a number of different isoforms and variants. Its secretion from pituitary somatotrophs is pulatile, with low or undetectable basal levels between peaks. GH secretion has a characteristic diurnal pattern with maximal levels recorded during sleep. Growth hormone is a powerful anabolic hormone that stimulates growth, cell reproduction, and cell regeneration in humans and other animals. The actions of GH are mediated by GH receptors (GHR), which are widely distributed among tissues. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
参考文献:
1. Strobl JS. et al.(1994) Pharmacol Rev. 46(1):1-34. 2. Baumann GP. et al. (2009) Growth Horm IGF Res. 19(4):333-40. 3. Catchpole HR. et al. (1980) JAMA. 243(7):652. 4. Murray RD. et al. (2000) Expert Opin Pharmacother.1(5):975-90
