• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
Use Able AI chat for product recommendations

Recombinant Human FOLR3 protein (rFc Tag) (HPLC verified)

种属

Human

纯度

>90 %, SDS-PAGE
>90 %, SEC-HPLC

标签

rFc Tag

生物活性

未测试

Cat no : Eg3170

Print datasheet

Synonyms

Folate receptor 3, folate receptor 3 (gamma), Folate receptor gamma, FR G, FR gamma

验证数据展示

  • Purity of Recombinant Human FOLR3 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Human FOLR3 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

  • The purity of Human FOLR3 was greater than 90% as determined by SEC-HPLC.

    The purity of Human FOLR3 was greater than 90% as determined by SEC-HPLC.

产品信息

纯度 >90 %, SDS-PAGE
>90 %, SEC-HPLC
内毒素 <0.1 EU/μg protein, LAL method
生物活性 
Not tested
来源 HEK293-derived Human FOLR3 protein Gln23-Ser245 (Accession# P41439-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 2352
蛋白编号 P41439-1
预测分子量 51.5 kDa
SDS-PAGE 55-65 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Folate receptor 3 (FOLR3) belongs to the folate receptor family. The folic acid receptors (FOLRs) have three isotypes (FOLR1, FOLR2 and FOLR3) in human. FOLR1 and FOLR2 are located in the cell membrane surface and transported folic acid into cell membrane using glycosylphosphatidylinositol (GPI)-anchored membrane protein by endocytosis. FOLR3 is mainly expressed in haematopoietic tissues, such as spleen and bone marrow, and its protein products are primarily secreted. FOLR3, which is expressed in humans but not in rodents, is a secreted protein that is elevated in the livers of patients with MASH but not in those with metabolic dysfunction–associated steatotic liver disease, those with type II diabetes, or healthy individuals.

参考文献:

1.Qu Y, et al. (2024) Respir Res. 25(1):59.
2.Shen F, et al. (1994) Biochemistry. 33(5):1209-15.
3.Shen F, et al. (1995) Biochemistry. 34(16):5660-5.
4.Quinn C, et al. (2023) Sci Transl Med. 15(715):eade2966.
||
New chat Able
正在加载，请稍候...