Recombinant Human FCGR2A/CD32a protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human FCGR2A protein Gln34-Gly217 (Accession# P12318-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 2212 |
| 蛋白编号 | P12318-1 |
| 预测分子量 | 46.4 kDa |
| SDS-PAGE | 50-60 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
IgG Fc receptors (FcγRs) play important roles in immune responses. Low-affinity IgG Fc receptor Fc gamma RIIa (FCGR2A, CD32a) is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils and is involved in the process of phagocytosis and clearing of immune complexes.
参考文献:
1.Gessner JE, et al. (1998) Ann Hematol.76(6):231-48. 2.Anania JC, et al. (2019) Front Immunol.19;10:464.
