Recombinant Human CTHRC1 protein (rFc Tag)

种属

Human

纯度

>90 %, SDS-PAGE

标签

rFc Tag

生物活性

未测试

Cat no : Eg2824

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Synonyms

CTHRC1, collagen triple helix repeat containing 1, Collagen triple helix repeat-containing protein 1, Protein NMTC1, UNQ762/PRO1550



产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性
Not tested
来源 HEK293-derived Human CTHRC1 protein Ser31-Lys243 (Accession# Q96CG8-1) with a rabbit IgG Fc tag at the C-terminus.
基因ID 115908
蛋白编号 Q96CG8-1
预测分子量 49.1 kDa
SDS-PAGE 46-55 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

CTHRC1 is a secreted glycoprotein that plays a pivotal role in extracellular matrix (ECM) deposition and wound repair. CTHRC1 is present in normal tissues and organs, and it has vital functions in physiological processes, including participating in the regulation of metabolism, arterial remodeling, bone formation and myelination of the peripheral nervous system. It has been reported that abnormal expression of CTHRC1 is involved in the carcinogenesis of various human organs, such as the breast, colon, pancreas, lung, stomach and liver.

参考文献:

1.Mei D. et al. (2020) Mediators Inflamm. 2020:9578701. 2.Myngbay A. et al. (2021) Int J Mol Sci. 22(5):2426.  3.Liu YJ. et al. (2023) Oncol Lett. 25(6):266. 4.Mukhatayev Z. et al. (2024) Cells. 13(11):946.