Recombinant Human CD44 protein (His Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
His Tag
生物活性
未测试
验证数据展示
产品信息
纯度 | >90 %, SDS-PAGE |
内毒素 | <0.1 EU/μg protein, LAL method |
生物活性 | Not tested |
来源 | HEK293-derived Human CD44 protein Gln21-Glu649 (Accession# P16070-1) with a His tag at the C-terminus. |
基因ID | 960 |
蛋白编号 | P16070-1 |
预测分子量 | 70.2 kDa |
SDS-PAGE | 85-125 kDa, reducing (R) conditions |
组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
CD44 is a type I transmembrane glycoprotein that mediates cell-cell and cell-matrix interactions through its affinity for hyaluronic acid (HA) and possibly also through its affinity for other ligands. Adhesion with HA plays an important role in cell migration, tumor growth and progression. CD44 is also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis.
参考文献:
1.Gomari MM.et al.(2021) Mutat Res Rev Mutat Res.787:108374. 2.Ponta H.et al.(1998) Int J Biochem Cell Biol.30(3):299-305. 3.Liu S.et al.(2023) Sci Rep.13(1):9657. 4.Gupta RC.et al.(2019) Front Vet Sci.6:192. 5.Chen S.et al.(2022) J Extracell Vesicles.11(3):e12203.