Recombinant Human BTN3A1 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human BTN3A1 protein Gln30-Gly254 (Accession# O00481-1) with a rabbit IgG Fc tag at the C-terminus. |
| 基因ID | 11119 |
| 蛋白编号 | O00481-1 |
| 预测分子量 | 50.4 kDa |
| SDS-PAGE | 48-62 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
BTN3A1, also named as Butyrophilin subfamily 3 member A1, BTF5 or CD277, is a 513 amino acid protein ,which contains one B30.2/SPRY domain and two Ig-like V-type (immunoglobulin-like) domains. BTN3A1 is involved in immunomodulation and binds to various receptors such as the γδ T cell receptor (γδTCR) and small molecules, fulfilling a wide range of functions including immunomodulation. BTN3A1 is also involved in the process of antigen presentation, influencing the recognition and response of immune cells to infections and tumors.
参考文献:
1. Herrmann T, et al. (2022). Front Immunol. 13:876493. 2. Payne KK, et al. (2020). Science. 369(6506):942-949. 3. Hu Y, et al. (2023). Signal Transduct Target Ther. 8(1):434.
