Recombinant Human C1QA protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human C1QA protein Glu23-Ala245 (Accession# P02745) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 712 |
| 蛋白编号 | P02745 |
| 预测分子量 | 50.9 kDa |
| SDS-PAGE | 52-65 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
The first component of complement, C1, is a calcium-dependent complex of the 3 subcomponents C1q, C1r, and C1s. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis.
参考文献:
1.Degn, Søren E et al. American journal of human genetics vol. 88,6 (2011): 689-705. 2.Reid, K B. The Biochemical journal vol. 141,1 (1974): 189-203. 3.Ling, Guang Sheng et al. Science (New York, N.Y.) vol. 360,6388 (2018): 558-563.
