Recombinant Human ANGPTL4 protein (rFc Tag)
种属
Human
纯度
>90 %, SDS-PAGE
标签
rFc Tag
生物活性
未测试
验证数据展示
产品信息
| 纯度 | >90 %, SDS-PAGE |
| 内毒素 | <0.1 EU/μg protein, LAL method |
| 生物活性 |
Not tested |
| 来源 | HEK293-derived Human ANGPTL4 protein Pro166-Ser406 (Accession# Q9BY76-1) with a rabbit IgG Fc tag at the N-terminus. |
| 基因ID | 51129 |
| 蛋白编号 | Q9BY76-1 |
| 预测分子量 | 53.9 kDa |
| SDS-PAGE | 57-70 kDa, reducing (R) conditions |
| 组分 | Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization. |
| 复溶 | Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water. |
| 储存条件 |
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
|
| 运输条件 | The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature. |
背景信息
ANGPTL4 is highly expressed in ATs and liver in humans and mice and to a lesser extent in heart, muscles and other tissues. Expression of ANGPTL4 is regulated by nutritional and metabolic states. For example, ANGPTL4 is induced by fasting and hypoxia in a tissue dependent manner. Its expression is under the regulation of several transcription factors including PPARs, glucocorticoid receptors, hypoxia-inducible factor 1-alpha (HIF1α) and others.
参考文献:
1. Yoon JC et al. (2000). Mol Cell Biol 20 (14), 5343–9. 2. Kersten S et al. (2000). J Biol Chem 275 (37), 28488–93. 3. Belanger AJ et al. (2002). J Mol Cell Cardiol 34 (7), 765–74. 4. Koliwad SK et al. (2009). J Biol Chem 284 (38), 25593–601.
