验证数据展示
产品信息
84128-5-PBS targets HER2/ErbB2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with mouse samples.
| 经测试应用 | WB, IF/ICC, Indirect ELISA Application Description |
| 经测试反应性 | mouse |
| 免疫原 |
Fusion Protein 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) |
| 别名 | Her2 / ErbB2, Her2, Erbb2, EC:2.7.10.1, CD340 |
| 计算分子量 | 139 kDa |
| 观测分子量 | 185 kDa |
| GenBank蛋白编号 | NM_001003817.1 |
| 基因名称 | Erbb2 |
| Gene ID (NCBI) | 13866 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purfication |
| UNIPROT ID | P70424 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Her2, or ErbB2, is a member of the EGF receptor family of receptor tyrosine kinases. It has no ligand-binding domain of its own. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signaling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase.
