验证数据展示
经过测试的应用
Positive WB detected in | Y79 cells, Transfected HEK-293 cells, Raji cells, L02 cells, K-562 cells, mouse lung tissue |
Positive IF/ICC detected in | HEK-293 cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:1000-1:4000 |
Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
15077-1-AP targets HPS1 in WB, IF/ICC, RIP, ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IF/ICC, ELISA Application Description |
文献引用应用 | WB, IF, RIP |
经测试反应性 | human |
文献引用反应性 | human, mouse |
免疫原 | HPS1 fusion protein Ag7149 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | Hermansky-Pudlak syndrome 1 |
别名 | HPS, Hermansky-Pudlak syndrome 1 protein, BLOC-3 complex member HPS1 |
计算分子量 | 79 kDa |
观测分子量 | 70-79 kDa |
GenBank蛋白编号 | BC000175 |
基因名称 | HPS1 |
Gene ID (NCBI) | 3257 |
RRID | AB_10694669 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q92902 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HPS1, also named as Hermansky-Pudlak syndrome 1 protein, is a 700 amino acid protein, which is a component of multiple cytoplasmic organelles. HPS1 is Apparently crucial for their normal development and function and involved in intracellular protein sorting.HPS1 is involved in the biogenesis of early melanosomes.
实验方案
Product Specific Protocols | |
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WB protocol for HPS1 antibody 15077-1-AP | Download protocol |
IF protocol for HPS1 antibody 15077-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Am J Respir Cell Mol Biol Gene-edited MLE-15 Cells as a Model for the Hermansky Pudlak Syndromes.
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Am J Respir Cell Mol Biol Dysregulation of Galectin-3: Implications for Hermansky-Pudlak Syndrome Pulmonary Fibrosis. | ||
Clin Exp Metastasis Long non-coding RNA NRSN2-AS1, transcribed by SOX2, promotes progression of esophageal squamous cell carcinoma by regulating the ubiquitin-degradation of PGK1. | ||
Mol Genet Metab In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer. | ||