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HOXA7 Monoclonal antibody, PBS Only

HOXA7 Monoclonal Antibody for WB, IF/ICC, ELISA
Cat No. 67112-1-PBS

产品说明书

CloneNo. 2A7H6

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IF/ICC, ELISA

HOX1.1, HOX1, Homeobox protein Hox-A7, Homeobox protein Hox-1A, ANTP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

67112-1-PBS targets HOXA7 in WB, IF/ICC, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, ELISA Application Description
经测试反应性 human
免疫原 HOXA7 fusion protein Ag19025 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 homeobox A7
别名 HOX1.1, HOX1, Homeobox protein Hox-A7, Homeobox protein Hox-1A, ANTP
计算分子量 230 aa, 25 kDa
观测分子量 20 kDa
GenBank蛋白编号BC148692
基因名称 HOXA7
Gene ID (NCBI) 3204
RRIDAB_2882416
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP31268
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

HOX genes play a fundamental role in the development of the vertebrate central nervous system, heart, axial skeleton, limbs, gut, urogenital tract and external genitalia. The homeobox gene Hoxa-1 is transcriptionally regulated by retinoic acid (RA) and encodes a transcription factor, which has been shown to play important roles in cell differentiation and embryogenesis. Hoxa-1 is also expressed in cancers, such as mammary tumors, though it is not expressed in normal gland or in precancerous mammary tissues. At embryonic stages, Hoxa-2 is expressed in the mesenchyme and epithelial cells of palate, however its expression is restricted to the tips of the growing palatal shelves. Hoxa-2 protein is predominantly expressed in the nuclei of cells in the ventral mantle region of the developing embryo. In the developing and adult mouse spinal cord, Hoxa-2 protein may contribute to dorsal-ventral patterning and/or to the specification of neuronal phenotype. Hoxa-7 functions as a potent transcriptional repressor and its action as such requires several domains, including both activator and repressor regions. Hoxa-7 is expressed in the fetal liver, lung, skeletal muscle, kidney, pancreas and placenta.

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