验证数据展示
经过测试的应用
| Positive WB detected in | HEK-293 cells, HeLa cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
26497-1-AP targets HOXA10 in WB, IHC, IF, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IHC, IF |
| 经测试反应性 | human |
| 文献引用反应性 | human, mouse, rat, monkey, bovine |
| 免疫原 |
CatNo: Ag24156 Product name: Recombinant human HOXA10 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 203-311 aa of BC013971 Sequence: YGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLGNSKGENAA 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | homeobox A10 |
| 别名 | homeobox A10, Homeobox protein Hox 1H, Homeobox protein Hox A10, Homeobox protein Hox-1.8, Homeobox protein Hox-1H |
| 计算分子量 | 393 aa, 41 kDa |
| 观测分子量 | 45-50 kDa |
| GenBank蛋白编号 | BC013971 |
| 基因名称 | HOXA10 |
| Gene ID (NCBI) | 3206 |
| RRID | AB_2880533 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P31260 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HOXA10, also named as Homeobox protein Hox-A10, is a 410 amino acid protein, which contains 1 homeobox DNA-binding domain and belongs to the Abd-B homeobox family. HOXA10 localizes in the nucleus and can Interacts with SIRT2. HOXA10 as sequence-specific transcription factor, is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. HoxA10 expression increases during the midsecretory phase of the menstrual cycle, which corresponds with increased levels of circulating progesterone.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for HOXA10 antibody 26497-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Mol Cancer LncHOXA10 drives liver TICs self-renewal and tumorigenesis via HOXA10 transcription activation.
| ||
Nat Cell Biol Segmental specification of the human female fetal reproductive tract revealed by spatiotemporal dynamics. | ||
J Adv Res Synergistic regulation of SLC7A11 and glucose-6-phosphate dehydrogenase in redox homeostasis governs decidualization: a mechanistic insight into adenomyosis-related infertility. | ||
Phytomedicine Bushen Zhuyun Recipe improves endometrial receptivity through kruppel-like factor 4-mediated recruitment of mixed-lineage leukemia 1 to activate homeobox A10 transcription. | ||
Cell Death Discov Polystyrene nanoparticles promote endometrial cancer development through the ACSS2-mediated reprogramming of arachidonic acid metabolism. | ||
J Transl Med CB2R agonism protects intestinal epithelium through β-catenin/HoxA10 loop in radiation injury. |
