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验证数据展示

  • WB analysis of Jurkat using 68558-1-Ig (same clone as 68558-1-PBS)

    WB analysis of Jurkat using 68558-1-Ig (same clone as 68558-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 68558-1-Ig (HELIOS antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68558-1-PBS in a different storage buffer formulation.

  • IP experiment of Jurkat using 68558-1-Ig (same clone as 68558-1-PBS)

    IP experiment of Jurkat using 68558-1-Ig (same clone as 68558-1-PBS)

    IP result of anti-HELIOS (IP:68558-1-Ig, 4ug; Detection:68558-1-Ig 1:3000) with Jurkat cells lysate 1560 ug. This data was developed using the same antibody clone with 68558-1-PBS in a different storage buffer formulation.

HELIOS Monoclonal antibody, PBS Only

HELIOS Monoclonal Antibody for WB, IP, Indirect ELISA
Cat No. 68558-1-PBS

产品说明书

CloneNo. 1F1F10

宿主/亚型

Mouse / IgG2b

种属反应性

Human

应用

WB, IP, Indirect ELISA

别名

HELIOS, IKZF2, Zinc finger protein Helios, ZNF1A2, ZNFN1A2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

68558-1-PBS targets HELIOS in WB, IP, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 Human
免疫原 HELIOS fusion protein Ag4357 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 IKAROS family zinc finger 2 (Helios)
别名 HELIOS, IKZF2, Zinc finger protein Helios, ZNF1A2, ZNFN1A2
计算分子量 500 aa, 57 kDa
观测分子量 65 kDa
GenBank蛋白编号BC028936
基因名称 HELIOS
Gene ID (NCBI) 22807
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9UKS7
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

IKZF2 (Helios), a member of the Ikaros transcription factor family, is expressed in a majority of Treg cells and some T cell and lymphocyte subsets. The expression of IKZF2 is associated with T cell activation and cellular division and is suggested a suitable marker to distinguish natural and induced Treg (PMID:21918685). IKZF2 plays a crucial role in maintaining function and stability of Treg cells, and IKZF2 deficiency reduces tumor growth in mice (PMID: 36863346).