验证数据展示
经过测试的应用
Positive WB detected in | Jurkat cells |
推荐稀释比
应用 | 推荐稀释比 |
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Western Blot (WB) | WB : 1:5000-1:50000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
83788-4-RR targets HDAC10 in WB, ELISA applications and shows reactivity with human samples.
经测试应用 | WB, ELISA Application Description |
经测试反应性 | human |
免疫原 | HDAC10 fusion protein Ag18851 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | histone deacetylase 10 |
别名 | Polyamine deacetylase HDAC10, HDAC 10, HD10, HD 10, EC:3.5.1.48 |
计算分子量 | 669 aa, 71 kDa |
观测分子量 | 70-75 kDa |
GenBank蛋白编号 | BC125083 |
基因名称 | HDAC10 |
Gene ID (NCBI) | 83933 |
RRID | AB_3671380 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | Q969S8 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
HDAC10, also named as Histone deacetylase 10, is a 669 amino acid protein, which is widely expressed with high levels in liver and kidney. HDAC10, which belongs to the class IIb subfamily, has an active deacetylase domain (DAC) and a catalytically inactive leucine-rich domain (LRD). HDAC10 is determined that it plays a role in homologous recombination, promotes autophagy and survival in neuroblastoma cells, suppresses cervical cancer metastasis and facilitates the cell cycle.
实验方案
Product Specific Protocols | |
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WB protocol for HDAC10 antibody 83788-4-RR | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |