验证数据展示
产品信息
21513-1-PBS targets HAND2 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag16038 Product name: Recombinant human HAND2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 1-64 aa of BC101406 Sequence: MSLVGGFPHHPVVHHEGYPFAAAAAASRCSHEENPYFHGWLIGHPEMSPPDYSMALSYSPEYAS 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | heart and neural crest derivatives expressed 2 |
| 别名 | bHLHa26, dHand, DHAND2, Hed, Thing2 |
| 计算分子量 | 217 aa, 24 kDa |
| 观测分子量 | 30-35 kDa |
| GenBank蛋白编号 | BC101406 |
| 基因名称 | HAND2 |
| Gene ID (NCBI) | 9464 |
| RRID | AB_3742040 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P61296 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
HAND2 is a bHLH transcription factor essential for cardiac morphogenesis, neural crest differentiation, and limb development. Acting in the nucleus, it regulates gene networks shaping embryonic heart structure, craniofacial patterning, and limb polarity. Dysregulation of HAND2 is linked to congenital heart defects, craniofacial disorders, and certain cancers, highlighting its importance in both development and disease.
