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Gsdmd Polyclonal antibody

Gsdmd Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, ELISA

Conjugate

Unconjugated

Cat No : 30695-1-AP

Print datasheet

Synonyms

1810036L03Rik, AW558049, DF5L, Dfna5l, gasdermin D, Gsdmd, Gsdmdc1, M2 4

验证数据展示

  • WB analysis using 30695-1-AP

    WB analysis using 30695-1-AP

    Various lysates were subjected to SDS PAGE followed by western blot with 30695-1-AP (Gsdmd antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inEL-4 cells, EL-4-B5 cells, NIH/3T3 cells, mouse liver tissue

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:2000-1:12000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

30695-1-AP targets Gsdmd in WB, ELISA applications and shows reactivity with mouse samples.

Tested Applications WB, ELISA
Tested Reactivity mouse
Immunogen Gsdmd fusion protein Ag33609 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name gasdermin D
Synonyms 1810036L03Rik, AW558049, DF5L, Dfna5l, gasdermin D, Gsdmd, Gsdmdc1, M2 4
Calculated Molecular Weight53 kDa
Observed Molecular Weight50-53 kDa
GenBank Accession NumberBC029813
Gene Symbol Gsdmd
Gene ID (NCBI) 69146
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9D8T2
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GSDMD is a member of the gasdermin family. Members of this family appear to play a role in regulation of epithelial proliferation. GSDMD has been suggested to act as a tumor suppressor. Recently, GSDMD is identified as a new component of inflammasomes, and it is an executor of pyroptosis and required for interleukin-1β secretion. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

实验方案

Product Specific Protocols
WB protocol for Gsdmd antibody 30695-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols