验证数据展示
产品信息
67272-1-PBS targets Granzyme K in IHC, IF-P, ELISA applications and shows reactivity with human samples.
经测试应用 | IHC, IF-P, ELISA Application Description |
经测试反应性 | human |
免疫原 | Granzyme K fusion protein Ag27297 种属同源性预测 |
宿主/亚型 | Mouse / IgG2b |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | granzyme K (granzyme 3; NK tryptase II) |
别名 | GZMK, Granzyme3, Granzyme 3, Fragmentin-3, Fragmentin 3 |
计算分子量 | 29 kDa |
GenBank蛋白编号 | BC035802 |
基因名称 | GZMK |
Gene ID (NCBI) | 3003 |
RRID | AB_2882541 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
UNIPROT ID | P49863 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Granzymes are a family of serine proteases stored in granules inside cytotoxic cells of the immune system. There are five human granzymes (granzyme A (GrA), GrB, GrH, GrK and GrM) currently identified, whereas mice have ten known granzymes (GrA-G, GrK, GrM and GrN) (PMID:14499263). Human GrK was first discovered in 1988 after purification from human peripheral blood mononuclear cells. GrK is expressed by cytotoxic T lymphocytes, natural killer T cells (NKT), γδ T cells and CD56bright+ NK cells.