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验证数据展示

  • WB analysis of mouse small intestine using 87897-1-RR (same clone as 87897-1-PBS)

    WB analysis of mouse small intestine using 87897-1-RR (same clone as 87897-1-PBS)

    mouse small intestine tissue were subjected to SDS PAGE followed by western blot with 87897-1-RR (Galectin 2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 87897-1-PBS in a different storage buffer formulation.

  • IHC staining of human tonsil using 87897-1-RR (same clone as 87897-1-PBS)

    IHC staining of human tonsil using 87897-1-RR (same clone as 87897-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsil tissue slide using 87897-1-RR (Galectin 2 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 87897-1-PBS in a different storage buffer formulation.

  • Affinity of 87897-1-RR

    Affinity of 87897-1-RR

    Biolayer interferometry (BLI) kinetic assays of 87897-1-RR against Human Galectin 2 were performed. The affinity constant is below 1 pM.

Galectin 2 Recombinant monoclonal antibody, PBS Only

Galectin 2 Uni-rAb® Recombinant Antibody for WB, IHC, Indirect ELISA
Cat No. 87897-1-PBS

产品说明书

CloneNo. 260048G3

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, IHC, Indirect ELISA

别名

Beta-galactoside-binding lectin L-14-II, Gal 2, Gal-2, HL14, Lactose binding lectin 2

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

87897-1-PBS targets Galectin 2 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Eg7632

Product name: Recombinant human LGALS2 protein

Source: mammalian cells-derived, pHZ-KIsec-N-rFc

Tag: N-rFc

Domain: 2-132 aa of BC059782

Sequence: TGELEVKNMDMKPGSTLKITGSIADGTDGFVINLGQGTDKLNLHFNPRFSESTIVCNSLDGSNWGQEQREDHLCFSPGSEVKFTVTFESDKFKVKLPDGHELTFPNRLGHSHLSYLSVRGGFNMSSFKLKE

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 lectin, galactoside-binding, soluble, 2
别名 Beta-galactoside-binding lectin L-14-II, Gal 2, Gal-2, HL14, Lactose binding lectin 2
计算分子量15 kDa
观测分子量10-15 kDa
GenBank蛋白编号BC059782
基因名称 Galectin 2
Gene ID (NCBI) 3957
RRIDAB_3745814
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDP05162
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Galectins are a class of carbohydrate-binding proteins implicated in multiple physiological processes including inflammation, immune responses, cell migration, autophagy and signal transduction (PMID: 29717004). Galectin-2 (Gal-2, also known as LGALS2) is a monocyte-derived carbohydrate-binding lectin; its upregulation correlates with reduced collateral arteriogenesis in patients with obstructive coronary artery disease (PMID: 25884209). Additionally, Gal-2 may interact with T cells, particularly in the setting of inflammatory bowel disease (PMID: 15356130).

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