GUCY2C Polyclonal antibody
GUCY2C Polyclonal Antibody for ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
ELISA
Conjugate
Unconjugated
验证数据展示
产品信息
The immunogen of 23011-1-AP is GUCY2C Fusion Protein expressed in E. coli.
Tested Applications | ELISA |
Tested Reactivity | human |
Immunogen | GUCY2C fusion protein Ag19256 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | guanylate cyclase 2C (heat stable enterotoxin receptor) |
Synonyms | GC C, Guanylyl cyclase C, GUC2C, GUCY2C, hSTAR, Intestinal guanylate cyclase, STA receptor, STAR |
Calculated Molecular Weight | 1073 aa, 123 kDa |
GenBank Accession Number | BC136544 |
Gene Symbol | GUCY2C |
Gene ID (NCBI) | 2984 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen Affinity purified |
UNIPROT ID | P25092 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
GUCY2C is also named as GUC2C, STAR(Heat-stable enterotoxin receptor), Guanylyl cyclase C and belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the E.coli heat-stable enterotoxin and considered to be the true apical membrane receptor for the endogenous ligands uroguanylin and guanylin. GUCY2C is not present in the endocrine pancreas, but is localized exclusively to the ductal system which fully corresponds to the GUCY2C activity detected in the exocrine ductal system, but particularly not in islets of Langerhans. GUCY2C with a molecular mass of 130 kDa is detected in pancreatic and intestinal extracts.(PMID:11431160). The full length protein is 123 kDa and has a signal peptide and nine glycosylation sites.