验证数据展示
产品信息
31846-1-PBS targets GPR158 in WB, Indirect ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag34602 Product name: Recombinant human GPR158 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 24-417 aa of BC157124 Sequence: ASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAPWSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFLQATREESRILLQDLSSSAPHLANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEFRGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYHPGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLR 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | G protein-coupled receptor 158 |
| 别名 | |
| 计算分子量 | 135 kDa |
| 观测分子量 | 150 kDa |
| GenBank蛋白编号 | BC157124 |
| 基因名称 | GPR158 |
| Gene ID (NCBI) | 57512 |
| RRID | AB_3670127 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity Purification |
| UNIPROT ID | Q5T848 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
G protein-coupled receptors (GPCR) are the largest family of proteins encoded in mammalian genomes that detect extracellular signals to program cellular response, which are essential to understanding physiology, disease, and drug development (PMID: 29249361; 29298813). G protein-coupled receptor 158 (GPR158, also known as mGlyR) is a class C orphan GPCR prominently expressed in brain tissue, where it controls synapse formation and function (PMID: 22689652; 34793198). It can transduce signals by coupling to the regulator of protein signaling (RGS) proteins and be related to the development of major depressive disorder and prostate cancer (PMID: 36996198; 29419376; 25693195).
