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验证数据展示

  • IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    IHC staining of mouse kidney using 81632-1-RR (same clone as 81632-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 81632-1-RR (GPR126 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81632-1-PBS in a different storage buffer formulation.

GPR126 Recombinant antibody, PBS Only

GPR126 Uni-rAbTM Recombinant Antibody for IHC, Indirect ELISA
Cat No. 81632-1-PBS

产品说明书

CloneNo. 6M2

宿主/亚型

Rabbit / IgG

种属反应性

Human, mouse

应用

IHC, Indirect ELISA

别名

APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

81632-1-PBS targets GPR126 in IHC, Indirect ELISA applications and shows reactivity with Human, mouse samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 Human, mouse
免疫原 GPR126 fusion protein Ag12195 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 G protein-coupled receptor 126
别名 APG1, DREG, G protein coupled receptor 126, GPR126, PS1TP2, VIGR
计算分子量 1222 aa, 137 kDa
GenBank蛋白编号BC075798
基因名称 GPR126
Gene ID (NCBI) 57211
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ86SQ4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GPR126 (G protein-coupled receptor 126) is a member of the adhesion GPCR family. GPR126 is all widely expressed on stromal cells (PMID: 25713288). It is essential for normal differentiation of promyelinating Schwann cells and for normal myelination of axons (PMID: 24227709). GPR126 regulates neural, cardiac and ear development by G-protein- and/or N-terminus-dependent signaling (PMID: 24082093, PMID: 24067352). GPR126 also stimulates VEGF signaling and angiogenesis by modulating VEGF receptor 2 expression through STAT5 and GATA2 in endothelial cells.