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验证数据展示

  • IF Staining of RAW 264.7 using 31781-1-AP (same clone as 31781-1-PBS)

    IF Staining of RAW 264.7 using 31781-1-AP (same clone as 31781-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed RAW 264.7 cells using GPR112 antibody (31781-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 31781-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse colon using 31781-1-AP (same clone as 31781-1-PBS)

    IHC staining of mouse colon using 31781-1-AP (same clone as 31781-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 31781-1-AP (GPR112 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31781-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse colon using 31781-1-AP (same clone as 31781-1-PBS)

    IHC staining of mouse colon using 31781-1-AP (same clone as 31781-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 31781-1-AP (GPR112 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31781-1-PBS in a different storage buffer formulation.

GPR112 Polyclonal antibody, PBS Only

GPR112 Polyclonal Antibody for IHC, IF/ICC, Indirect ELISA
Cat No. 31781-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

IHC, IF/ICC, Indirect ELISA

别名

RP1 299I16, PGR17, G protein coupled receptor 112

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

31781-1-PBS targets GPR112 in IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse samples.

经测试应用 IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse
免疫原

CatNo: Ag36114

Product name: Recombinant human GPR112 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 2400-2550 aa of NM_153834

Sequence: KWLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFKQCKLLQELPDKIVDLANITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQCDEISMNLTHVMLQIINVVLEKQNNSASDLHEISNEILRIIERTGHKM

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 G protein-coupled receptor 112
别名 RP1 299I16, PGR17, G protein coupled receptor 112
计算分子量333kDa
GenBank蛋白编号NM_153834
基因名称 GPR112
Gene ID (NCBI) 139378
RRIDAB_3670112
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ8IZF6
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GPR112 is a member of the adhesion G protein-coupled receptor (aGPCR) family. These receptors are characterized by a complex architecture and large size, mainly attributed to their N terminus, which contains a variety of domains involved in cell-cell and cell-matrix interactions. The function of GPR112 and other aGPCRs is closely related to key aspects of the development, architecture, and function of the nervous system. They are involved in neuronal migration, axon guidance, dendritogenesis, and synaptogenesis. Additionally, aGPCRs, including GPR112, have been implicated in the development of myelinating glial cells, which are crucial for proper neuronal signal propagation.

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