验证数据展示
Planning an IHC experiment? We recommend our IHCeasy GNAI1 Ready-To-Use IHC Kit. GNAI1 primary antibody included.
产品信息
68266-1-PBS targets GNAI1 in WB, Indirect ELISA applications and shows reactivity with Mouse, Rat, Pig, Chicken samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | Mouse, Rat, Pig, Chicken |
| 免疫原 | GNAI1 fusion protein Ag3290 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG2b |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| 别名 | Gi, GNAI1 |
| 计算分子量 | 354 aa, 40 kDa |
| 观测分子量 | 38-40 kDa |
| GenBank蛋白编号 | BC026326 |
| 基因名称 | GNAI1 |
| Gene ID (NCBI) | 2770 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P63096 |
| 储存缓冲液 | PBS only , pH 7.3 |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The guanine nucleotide-binding protein G(i), α-1 subunit (GNAI1), also known as Gαi-1, belongs to the Gαi family. GNAI1 is an adenylate cyclase inhibitor that modulates cAMP. GNAI1 exerts inhibitory effects on cAMP production through its interaction with GPCR and the inactivation of adenyl cyclase (PMID: 35678269). GNAI1 has 2 isoforms with molecular weights of 35 and 40 kDa, respectively.
