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验证数据展示

  • WB analysis using 13381-1-AP (same clone as 13381-1-PBS)

    WB analysis using 13381-1-AP (same clone as 13381-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13381-1-AP (GLRX2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13381-1-PBS in a different storage buffer formulation.

  • IF Staining of MCF-7 using 13381-1-AP (same clone as 13381-1-PBS)

    IF Staining of MCF-7 using 13381-1-AP (same clone as 13381-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using GLRX2 antibody (13381-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 13381-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

GLRX2 Polyclonal antibody, PBS Only

GLRX2 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 13381-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

13381-1-PBS targets GLRX2 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag4218

Product name: Recombinant human GLRX2 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-148 aa of BC028113

Sequence: RSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glutaredoxin 2
别名
计算分子量 164 aa, 18 kDa
观测分子量 16 kDa
GenBank蛋白编号BC028113
基因名称 GLRX2
Gene ID (NCBI) 51022
RRIDAB_10643373
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9NS18
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GLRX2(Glutaredoxin-2) is also named as GRX2 and belongs to the glutaredoxin family. It facilitates the maintenance of cellular redox homeostasis upon treatment with apoptotic agents, thereby preventing cardiolipin oxidation and cytochrome C release. The GLRX2, which exists in a dynamic equilibrium of enzymatically active monomers and quiescent dimers,is a 16-kDa protein directed either to the nucleus or to the mitochondria through differential splicing of the first exon(PMID: 17121859). It has 2 isoforms produced by alternative splicing.

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