×
Use Able AI chat for product recommendations

验证数据展示

  • WB analysis using 32645-1-AP (same clone as 32645-1-PBS)

    WB analysis using 32645-1-AP (same clone as 32645-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 32645-1-AP (GLMN antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32645-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 32645-1-AP (same clone as 32645-1-PBS)

    IF Staining of HeLa using 32645-1-AP (same clone as 32645-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using GLMN antibody (32645-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 32645-1-PBS in a different storage buffer formulation.

GLMN Polyclonal antibody, PBS Only

GLMN Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 32645-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

FAP, FAP48, FAP68, FK506-binding protein-associated protein, FKBP-associated protein

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

点击咨询售前客服

点击咨询售后客服

产品信息

32645-1-PBS targets GLMN in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag37763

Product name: Recombinant human GLMN protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 241-594 aa of BC001257

Sequence: ASEIIGFLSAIGHPFPKMIFNHGRKKRTWNYLEFEEEENKQLADSMASLAYLVFVQGIHIDQLPMVLSPLYLLQFNMGHIEVFLQRTEESVISKGLELLENSLLRIEDNSLLYQYLEIKSFLTVPQGLVKVMTLCPIETLRKKSLAMLQLYINKLDSQGKYTLFRCLLNTSNHSGVEAFIIQNIKNQIDMSLKRTRNNKWFTGPQLISLLDLVLFLPEGAETDLLQNSDRIMASLNLLRYLVIKDNENDNQTGLWTELGNIENNFLKPLHIGLNMSKAHYEAEIKNSQEAQKSKDLCSITVSGEEIPNMPPEMQLKVLHSALFTFDLIESVLARVEELIEIKTKSTSEENIGIK

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glomulin, FKBP associated protein
别名 FAP, FAP48, FAP68, FK506-binding protein-associated protein, FKBP-associated protein
计算分子量 68 kDa
观测分子量 68 kDa
GenBank蛋白编号BC001257
基因名称 GLMN
Gene ID (NCBI) 11146
RRIDAB_3742689
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity Purification
UNIPROT IDQ92990
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Glomulin (GLMN) is a regulatory component of cullin-RING-based SCF (SKP1-Cullin-F-box protein) E3 ubiquitin-protein ligase complexes (PMID: 22405651; 22748924). It inhibits E3 ubiquitin ligase activity by binding to RBX1 (via the RING domain) and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34 (PMID: 22405651; 22748924). GLMN is essential for normal vasculature development and contributes to the regulation of RPS6KB1 phosphorylation (PMID: 11845407; 11571281).

||
New chat

Able™

正在加载，请稍候...