验证数据展示
Planning an IHC experiment? We recommend our IHCeasy GIT2 Ready-To-Use IHC Kit. GIT2 primary antibody included.
产品信息
10339-1-AP targets GIT2 in ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | GIT2 fusion protein Ag0321 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| 别名 | ARF GAP GIT2, CAT 2, CAT2, GIT2, GRK interacting protein 2, KIAA0148 |
| 计算分子量 | 95 kDa |
| GenBank蛋白编号 | BC001379 |
| 基因名称 | GIT2 |
| Gene ID (NCBI) | 9815 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q14161 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
G protein-coupled receptor kinase-interacting protein 2(GIT2) is a signaling scaffold protein involved in the regulation of membrane trafficking, cytoskeletal structure, and G protein-coupled receptor internalization. It belongs to the GIT fmaily that has been shown to involve in regrlating emotional function, vascular development and mitochondrial biogenesis. Also GIT protein may have role in focal adhesion dynamics, cell migration and directing the spatial localization of signaling molecules such as MEK1 and ERK1/2.