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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 86016-1-RR (same clone as 86016-1-PBS)

    WB analysis using 86016-1-RR (same clone as 86016-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86016-1-RR (KCNJ6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86016-1-PBS in a different storage buffer formulation.

  • WB analysis using 86016-1-RR (same clone as 86016-1-PBS)

    WB analysis using 86016-1-RR (same clone as 86016-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86016-1-RR (KCNJ6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86016-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86016-1-RR

    Affinity and Kinetic Characterization of 86016-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86016-1-RR against Human GIRK2 were performed. The affinity constant is 0.372 nM.

GIRK2 Recombinant antibody, PBS Only

GIRK2 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 86016-1-PBS

产品说明书

CloneNo. 250605D1

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

KCNJ6, BIR1, G protein-activated inward rectifier potassium channel 2, GIRK 2, GIRK-2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

86016-1-PBS targets GIRK2 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 GIRK2 fusion protein Ag16344 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 potassium inwardly-rectifying channel, subfamily J, member 6
别名 KCNJ6, BIR1, G protein-activated inward rectifier potassium channel 2, GIRK 2, GIRK-2
计算分子量 423 aa, 48 kDa
观测分子量 45-48 kDa
GenBank蛋白编号BC101547
基因名称 GIRK2
Gene ID (NCBI) 3763
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP48051
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GIRK2 (also known as Kir3.2), encoded by KCNJ6 gene, is a member of the G protein-coupled inwardly-rectifying potassium channel (GIRK, Kir3) family of inward rectifier potassium channels. GIRK channels are activated following stimulation of G protein-coupled receptors (PMID: 26422984). They play important roles in regulating cellular excitabilities in the heart and brain (PMID: 31043612). Mutations in KCNJ6 gene are associated with Keppen-Lubinsky Syndrome (PMID: 25620207).