GGTLC2 Polyclonal antibody

GGTLC2 Polyclonal Antibody for WB, ELISA
Cat No. 18191-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse

应用

WB, ELISA

Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTL4, Glutathione hydrolase light chain 2

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -


经过测试的应用

Positive WB detected in786-O cells, human urine sample, human milk, mouse kidney tissue

推荐稀释比

应用推荐稀释比
Western Blot (WB)WB : 1:1000-1:6000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

18191-1-AP targets GGTLC2 in WB, ELISA applications and shows reactivity with human, mouse samples.

经测试应用 WB, ELISA Application Description
经测试反应性 human, mouse
免疫原 GGTLC2 fusion protein Ag12911 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gamma-glutamyltransferase light chain 2
别名 Gamma-glutamyltransferase light chain 2, Gamma-glutamyltransferase-like protein 4, GGTL4, Glutathione hydrolase light chain 2
计算分子量 218 aa, 24 kDa
观测分子量24 kDa
GenBank蛋白编号BC069534
基因名称 GGTLC2
Gene ID (NCBI) 91227
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ14390
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

GGT is a protease anchored to the cell membrane, consisting of a light chain and a heavy chain. GGTLC2 (Glutathione hydrolase light chain 2), also known as GGTL4, a constituent of the GGT family, has been characterized as an antioxidant gene, with emerging evidence indicating a potential link between its expression levels and sarcoma patient outcome (PMID: 40191433). Studies have shown that GGTLC2 is highly expressed in gastric cancer, promoting cell proliferation, invasion, and migration while inhibiting apoptosis and ferroptosis.

实验方案

Product Specific Protocols
WB protocol for GGTLC2 antibody 18191-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols
Loading...