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验证数据展示

  • WB analysis of HepG2 using 83392-3-RR (same clone as 83392-3-PBS)

    WB analysis of HepG2 using 83392-3-RR (same clone as 83392-3-PBS)

    WB result of GGTLC1 antibody (83392-3-RR; 1:1200; incubated at room temperature for 1.5 hours) with sh-Control and sh-GGTLC1 transfected HepG2 cells. This data was developed using the same antibody clone with 83392-3-PBS in a different storage buffer formulation.

  • WB analysis using 83392-3-RR (same clone as 83392-3-PBS)

    WB analysis using 83392-3-RR (same clone as 83392-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83392-3-RR (GGTLC1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83392-3-PBS in a different storage buffer formulation.

  • Cytometric bead array standard curve of MP00433-2

    Cytometric bead array standard curve of MP00433-2

    Cytometric bead array standard curve of MP00433-2, GGTLC1 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 83392-2-PBS. Detection antibody: 83392-3-PBS. Standard: Ag11592. Range: 0.625-80 ng/mL.

  • Affinity and Kinetic Characterization of 83392-3-RR

    Affinity and Kinetic Characterization of 83392-3-RR

    Biolayer interferometry (BLl) kinetic assays of 83392-3-RR against Human GGTLC1 were performed. The affinity constant is below 1 pM.

  • Featured Product
  • KD/KO验证

GGTLC1 Recombinant antibody, PBS Only (Detector)

GGTLC1 Uni-rAbTM Recombinant Antibody for WB, Cytometric bead array, Indirect ELISA
Cat No. 83392-3-PBS

产品说明书

CloneNo. 240297D9

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, Cytometric bead array, Indirect ELISA

别名

240297D9, Gamma-glutamyltransferase light chain 1, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase-like protein 6, GGTL6

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

83392-3-PBS targets GGTLC1 as part of a matched antibody pair:

MP00433-2: 83392-2-PBS capture and 83392-3-PBS detection (validated in Cytometric bead array)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 WB, Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 GGTLC1 fusion protein Ag11592 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 gamma-glutamyltransferase light chain 1
别名 240297D9, Gamma-glutamyltransferase light chain 1, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase-like protein 6, GGTL6
计算分子量 225 aa, 24 kDa
观测分子量20-24 kDa
GenBank蛋白编号BC040904
基因名称 GGTLC1
Gene ID (NCBI) 92086
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ9BX51
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).