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验证数据展示

  • WB analysis of HepG2 using 17537-1-AP (same clone as 17537-1-PBS)

    WB analysis of HepG2 using 17537-1-AP (same clone as 17537-1-PBS)

    WB result of GGTLC1 antibody (17537-1-AP; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-GGTLC1 transfected HepG2 cells. This data was developed using the same antibody clone with 17537-1-PBS in a different storage buffer formulation.

  • WB analysis using 17537-1-AP (same clone as 17537-1-PBS)

    WB analysis using 17537-1-AP (same clone as 17537-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17537-1-AP (GGTLC1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17537-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 17537-1-AP (same clone as 17537-1-PBS)

    IF Staining of HepG2 using 17537-1-AP (same clone as 17537-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using GGTLC1 antibody (17537-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 17537-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO Validated

GGTLC1 Polyclonal antibody, PBS Only

GGTLC1 Polyclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 17537-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

Gamma-glutamyltransferase light chain 1, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase-like protein 6, GGTL6, GGTLA4

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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产品信息

17537-1-PBS targets GGTLC1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag11592

Product name: Recombinant human GGTLC1 protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-225 aa of BC040904

Sequence: MTSEFFSAQLRAQISDDTTHPISYYKPEFYMPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILLNNEMDDFSSTSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITMATALAIIYNLWFGYDVKWAVEEPRLHNQLLPNVTTVERNIDQEVTAALETRHHHTQITSTFIAVVQAIVRMAGGWAAASDSRKGGEPAGY

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 gamma-glutamyltransferase light chain 1
别名 Gamma-glutamyltransferase light chain 1, Gamma-glutamyltransferase-like activity 4, Gamma-glutamyltransferase-like protein 6, GGTL6, GGTLA4
计算分子量 225 aa, 24 kDa
观测分子量24 kDa
GenBank蛋白编号BC040904
基因名称 GGTLC1
Gene ID (NCBI) 92086
RRIDAB_3669277
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9BX51
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Gamma-glutamyltransferase light chain 1 (GGTLC1), initially named GGTL6, then GGTLA4, and later GGTLC1 in 2008, is a member of the gamma-glutamyl transferase (GGT) family. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. Knockdown of GGTLC1 in Endometrial cancer (EC) cells was shown to induce G0/G1 phase arrest and apoptosis, underscoring the significance of GGTLC1 as a key regulator of these cellular processes in EC (PMID: 38841516).

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