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验证数据展示

  • WB analysis using 68340-1-Ig (same clone as 68340-1-PBS)

    WB analysis using 68340-1-Ig (same clone as 68340-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68340-1-Ig (GDAP1L1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68340-1-PBS in a different storage buffer formulation.

  • IF Staining of Neuro-2a using 68340-1-Ig (same clone as 68340-1-PBS)

    IF Staining of Neuro-2a using 68340-1-Ig (same clone as 68340-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Neuro-2a cells using GDAP1L1 antibody (68340-1-Ig, Clone: 1C7A3 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1). This data was developed using the same antibody clone with 68340-1-PBS in a different storage buffer formulation.

  • IF Staining of SH-SY5Y using 68340-1-Ig (same clone as 68340-1-PBS)

    IF Staining of SH-SY5Y using 68340-1-Ig (same clone as 68340-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed SH-SY5Y cells using GDAP1L1 antibody (68340-1-Ig, Clone: 1C7A3 ) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Mouse Recombinant Secondary Antibody (H+L) (RGAM002). This data was developed using the same antibody clone with 68340-1-PBS in a different storage buffer formulation.

GDAP1L1 Monoclonal antibody, PBS Only

GDAP1L1 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 68340-1-PBS

产品说明书

CloneNo. 1C7A3

宿主/亚型

Mouse / IgG2b

种属反应性

human, mouse, rat, pig, rabbit

应用

WB, IF/ICC, Indirect ELISA

别名

1C7A3, Ganglioside-induced differentiation-associated protein 1-like 1, GDAP1 L1, GDAP1-L1

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

68340-1-PBS targets GDAP1L1 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, pig, rabbit
免疫原

CatNo: Ag27717

Product name: Recombinant human GDAP1L1 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-367 aa of BC009014

Sequence: MATPNNLTPTNCSWWPISALESDAAKPAEAPDAPEAASPAHWPRESLVLYHWTQSFSSQKVRLVIAEKGLVCEERDVSLPQSEHKEPWFMRLNLGEEVPVIIHRDNIISDYDQIIDYVERTFTGEHVVALMPEVGSLQHARVLQYRELLDALPMDAYTHGCILHPELTTDSMIPKYATAEIRRHLANATTDLMKLDHEEEPQLSEPYLSKQKKLMAKILEHDDVSYLKKILGELAMVLDQIEAELEKRKLENEGQKCELWLCGCAFTLADVLLGATLHRLKFLGLSKKYWEDGSRPNLQSFFERVQRRFAFRKVLGDIHTTLLSAVIPNAFRLVKRKPPSFFGASFLMGSLGGMGYFAYWYLKKKYI

种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 ganglioside-induced differentiation-associated protein 1-like 1
别名 1C7A3, Ganglioside-induced differentiation-associated protein 1-like 1, GDAP1 L1, GDAP1-L1
计算分子量 367 aa, 42 kDa
观测分子量 38-40 kDa
GenBank蛋白编号BC009014
基因名称 GDAP1L1
Gene ID (NCBI) 78997
偶联类型 Unconjugated
形式Liquid
纯化方式Protein A purification
UNIPROT IDQ96MZ0
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Ganglioside-induced differentiation-associated protein 1-like 1 (GDAP1L1) belongs to GST superfamily. Owing to its central role in mitochondrial fission, GDAP1L1 is a homologue of GDAP1 implicated in cellular processes, such as cell death, autophagy, aging, and immune response regulation (PMID:32230997). GDAP1L1, a fission factor controlling mitochondrial fission, induces fission upon translocation from the cytosol to mitochondria in response to stress condition (PMID:34638757). Furthermore, the activity of GDAP1L1 is dependent on Drp1. GDAP1, a paralog of GDAP1L1, evokes mitochondrial fragmentation only in the presence of Drp1 in HeLa cells (PMID:19782751).

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