验证数据展示
产品信息
16980-1-AP targets GBA3 in ELISA applications and shows reactivity with human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 |
CatNo: Ag9936 Product name: Recombinant human GBA3 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 1-162 aa of BC029362 Sequence: MAFPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEEDLKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | glucosidase, beta, acid 3 (cytosolic) |
| 别名 | CBG, CBGL1, Cytosolic beta glucosidase, GBA3, GLUC, KLrP |
| 计算分子量 | 18 kDa, 54 kDa |
| GenBank蛋白编号 | BC029362 |
| 基因名称 | GBA3 |
| Gene ID (NCBI) | 57733 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9H227 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
GBA3(cytosolic beta-glucosidase) is also named as CBG, CBGL1 and belongs to the glycosyl hydrolase 1 family and Klotho subfamily. It catalyses the hydrolysis of O-linkedβ-glycosidic bonds at the non-reducing end of carbohydrates with retention of anomeric configuration. It is a 53-kDa monomeric protein with a pI of 4.7-4.8, present in the liver, kidney, intestine and spleen of humans(PMID:12667141). It has 2 isoforms produced by alternative splicing.