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验证数据展示

  • WB analysis of mouse kidney using 12801-1-AP (same clone as 12801-1-PBS)

    WB analysis of mouse kidney using 12801-1-AP (same clone as 12801-1-PBS)

    mouse kidney tissue were subjected to SDS PAGE followed by western blot with 12801-1-AP (GATM antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12801-1-PBS in a different storage buffer formulation.

  • IHC staining of human pancreas cancer using 12801-1-AP (same clone as 12801-1-PBS)

    IHC staining of human pancreas cancer using 12801-1-AP (same clone as 12801-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer using 12801-1-AP (GATM antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12801-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with GATM antibody included

GATM Polyclonal antibody, PBS Only

GATM Polyclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 12801-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, Indirect ELISA

别名

缓冲液配方: 
PBS, Azide, Glycerol
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy GATM Ready-To-Use IHC Kit. GATM primary antibody included.

产品信息

12801-1-PBS targets GATM in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原

CatNo: Ag3754

Product name: Recombinant human GATM protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 74-423 aa of BC004141

Sequence: PLEEVIVGRAENACVPPFTIEVKANTYEKYWPFYQKQGGHYFPKDHLKKAVAEIEEMCNILKTEGVTVRRPDPIDWSLKYKTPDFESTGLYSAMPRDILIVVGNEIIEAPMAWRSRFFEYRAYRSIIKDYFHRGAKWTTAPKPTMADELYNQDYPIHSVEDRHKLAAQGKFVTTEFEPCFDAADFIRAGRDIFAQRSQVTNYLGIEWMRRHLAPDYRVHIISFKDPNPMHIDATFNIIGPGIVLSNPDRPCHQIDLFKKAGWTIITPPTPIIPDDHPLWMSSKWLSMNVLMLDEKRVMVDANEVPIQKMFEKLGITTIKVNIRNANSLGGGFHCWTCDVRRRGTLQSYLD

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 glycine amidinotransferase (L-arginine:glycine amidinotransferase)
别名
计算分子量 423 aa, 48 kDa
观测分子量 48 kDa
GenBank蛋白编号BC004141
基因名称 GATM
Gene ID (NCBI) 2628
RRIDAB_2109060
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP50440
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GATM, also known as AGAT, produces ornithine and guanidinoacetate (GAA) from arginine and glycine, and is a key enzyme for creatine synthesis. GATM deficiency in early infancy causes neurodevelopmental delay. GATM is predominantly expressed in kidney and pancreas in adults. Decrease of GAMT proteins was observed in proximal tubule damage cases, which links GATM as a general marker for proximal tubule damage. Alternative splicing of GATM generates three isoforms with molecular weights between 44 kDa to 48 kDa.

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