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验证数据展示

  • WB analysis of human cerebellum using 85750-1-RR (same clone as 85750-1-PBS)

    WB analysis of human cerebellum using 85750-1-RR (same clone as 85750-1-PBS)

    human cerebellum tissue were subjected to SDS PAGE followed by western blot with 85750-1-RR (GAD2 antibody) at dilution of 1:30000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85750-1-PBS in a different storage buffer formulation.

  • WB analysis using 85750-1-RR (same clone as 85750-1-PBS)

    WB analysis using 85750-1-RR (same clone as 85750-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85750-1-RR (GAD2 antibody) at dilution of 1:300000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85750-1-PBS in a different storage buffer formulation.

GAD65 Recombinant antibody, PBS Only

GAD65 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Cat No. 85750-1-PBS

产品说明书

CloneNo. 250044B5

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, Indirect ELISA

别名

GAD2, EC:4.1.1.15, GAD 65, GAD-65

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

85750-1-PBS targets GAD65 in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Peptide 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
别名 GAD2, EC:4.1.1.15, GAD 65, GAD-65
计算分子量 65 kDa
观测分子量65 kDa
GenBank蛋白编号NM_000818
基因名称 GAD65
Gene ID (NCBI) 2572
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ05329
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GAD2, also named as GAD65, belongs to the group II decarboxylase family. GAD2 catalyzes the production of GABA. It is responsible for the synthesis of the essential neurotransmitter gamma-aminobutyric acid (GABA) from L-glutamic acid. GAD2 is expressed in nervous and endocrine systems and are thought to be involved in synaptic transmission and INS secretion. Autoantibodies against GAD2 may serve as markers for type I diabetes. Many individuals suffering from an adult onset disorder known as Stiff Person Syndrome (SPS) also express autoantibodies to GAD2. The antibody is specific to GAD2.