验证数据展示
经过测试的应用
| Positive WB detected in | mouse brain tissue, mouse skeletal muscle tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
25899-1-AP targets GABRR1 in WB, IF, IP, CoIP, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 文献引用应用 | WB, IF, IP, CoIP |
| 经测试反应性 | human, mouse |
| 文献引用反应性 | mouse |
| 免疫原 |
CatNo: Ag23165 Product name: Recombinant human GABRR1 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 19-78 aa of BC130344 Sequence: RMHWPGREVHEMSKKGSRPQRQRREVHEDAHKQVSPILRRSPDITKSPLTKSEQLLRIDD 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | gamma-aminobutyric acid (GABA) receptor, rho 1 |
| 别名 | GABA(A) receptor subunit rho 1, GABA(C) receptor, GABRR1 |
| 计算分子量 | 479 aa, 56 kDa |
| 观测分子量 | 50-56 kDa |
| GenBank蛋白编号 | BC130344 |
| 基因名称 | GABRR1 |
| Gene ID (NCBI) | 2569 |
| RRID | AB_2880290 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P24046 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
GABRR1 is a member of a family of ligand-gated chloride channels that are the major inhibitory neurotransmitter receptors in the central nervous system. GABRR1 acts as a rho-1 receptor of GABA, the major inhibitory neurotransmitter in the vertebrate brain, may play a role in retinal neurotransmission. And then, GABRR1 is highly expressed in the retina and in a lesser extent in brain, lung and thymus. There are 3 isoforms for GABRR1 produced by alternative splicing, with the molecular weights of 46 kDa, 53 kDa, 56 kDa, respectively.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for GABRR1 antibody 25899-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Insect Sci Rho 1 participates in parasitoid wasp eggs maturation and host cellular immunity inhibition | ||
Biochem Biophys Res Commun Extraction method combining saponin and trehalose useful for analyzing fragile intermolecular association | ||
Transl Psychiatry Acute stress induces severe neural inflammation and overactivation of glucocorticoid signaling in interleukin-18-deficient mice |
