验证数据展示
产品信息
83030-4-RR targets GABRA4 in ELISA applications and shows reactivity with Human samples.
| 经测试应用 | ELISA Application Description |
| 经测试反应性 | Human |
| 免疫原 |
CatNo: Ag3600 Product name: Recombinant human GABRA4 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 338-554 aa of BC035055 Sequence: AAVNYFTNIQMEKAKRKTSKPPQEVPAAPVQREKHPEAPLQNTNANLNMRKRTNALVHSESDVGNRTEVGNHSSKSSTVVQESSKGTPRSYLASSPNPFSRANAAETISAARALPSASPTSIRTGYMPRKASVGSASTRHVFGSRLQRIKTTVNTIGATGKLSATPPPSAPPPSGSGTSKIDKYARILFPVTFGAFNMVYWVVYLSKDTMEKSESLM 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| 别名 | GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4, 230302A4, GABA A Receptor alpha 4, GABA(A) receptor subunit alpha-4, GABAA Receptor alpha 4, GABAAR subunit alpha-4 |
| 计算分子量 | 554 aa, 62 kDa |
| 观测分子量 | 62-70 kDa |
| GenBank蛋白编号 | BC035055 |
| 基因名称 | GABRA4 |
| Gene ID (NCBI) | 2557 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | P48169 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABRA4, encoding the extrasynaptically located α4‐subunit of the GABAA receptor, is involved in the etiology of autism. (PMID: 32028044, 32033586)
