验证数据展示
产品信息
28535-1-PBS targets GABRA2 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| 经测试应用 | WB, Indirect ELISA Application Description |
| 经测试反应性 | human, rat |
| 免疫原 |
CatNo: Ag29301 Product name: Recombinant human GABRA2 protein Source: e coli.-derived, PGEX-4T Tag: GST Domain: 348-412 aa of NM_000807 Sequence: SVVNDKKKEKASVMIQNNAYAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFN 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| 别名 | GABA(A) receptor subunit alpha-2, GABAAR subunit alpha-2, Gamma-aminobutyric acid receptor subunit alpha-2 |
| 计算分子量 | 51 kDa |
| 观测分子量 | 51 kDa |
| GenBank蛋白编号 | NM_000807 |
| 基因名称 | GABRA2 |
| Gene ID (NCBI) | 2555 |
| RRID | AB_3742295 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P47869 |
| 储存缓冲液 | PBS only, pH 7.3. |
| 储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
GABRA2 (gamma-aminobutyric acid type A receptor subunit alpha2), also known as DEE78. It is expected to be located in cell membrane, and the protein is highly expressed in brain. The protein is a ligand-gated chloride channel, which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:29961870). It also plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA-gated ion channel (PubMed:29961870). The calculated molecular weight of GABRA2 is 51 kDa.
