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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse Fas/CD95 Rabbit Recombinant Antibody (98135-1-RR, Clone: 241229C11) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse CD8a (53-6.7) (APC-65069, Clone: 53-6.7). Cells were not fixed. This data was developed using the same antibody clone with 98135-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    FC experiment of mouse thymocytes using 98135-1-RR (same clone as 98135-1-PBS)

    1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse Fas/CD95 Rabbit Recombinant Antibody (98135-1-RR, Clone: 241229C11) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98135-1-PBS in a different storage buffer formulation.

Anti-Mouse Fas/CD95 Rabbit Recombinant Antibody, PBS Only

Fas/CD95 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98135-1-PBS

产品说明书

CloneNo. 241229C11

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

Fas, CD95, TNFR6, APT1, APO 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98135-1-PBS targets Fas/CD95 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 FusionProtein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 Fas (TNF receptor superfamily member 6)
别名 Fas, CD95, TNFR6, APT1, APO 1
计算分子量37kDa
GenBank蛋白编号NM_007987.2
基因名称 Fas/CD95
Gene ID (NCBI) 14102
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP25446
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains, leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The molecular mass of native Fas is 38 kDa, the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.